At what point in meiosis II do the centromeres divide?

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During meiosis II, the correct point at which the centromeres divide is in anaphase. Anaphase is characterized by the separation of sister chromatids that are connected at their centromeres. When the centromeres divide, the sister chromatids are pulled apart toward opposite poles of the cell by the spindle fibers. This process ensures that each newly forming gamete will receive one copy of each chromosome.

The other stages, such as prophase, telophase, and metaphase, do not involve the division of centromeres. In prophase, the chromatids condense and the nuclear envelope begins to break down, but no separation occurs yet. In telophase, the separated chromosomes reach the poles and begin to unwind, and the nuclear envelope re-forms. During metaphase, the chromosomes align at the cell equator, but centromeres remain intact, holding sister chromatids together. Thus, the process of centromere division specifically marks the transition into anaphase during meiosis II.

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